Purified Anti-Human TYRP1 Antibody[TA99], Functional Grade (AN007880)
![Purified Anti-Human TYRP1 Antibody[TA99], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human TYRP1 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Activ Reported in the literature |
| Isotype | Rabbit IgG, κ |
| Host | Rabbit |
| Reactivity | Human |
| Applications | FCM, Activ |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human TYRP1 protein |
| Abbre | TYRP1 |
| Synonyms | OCA, CAS, b-PROTEIN, CATB, GP75, OCA3, TRP, TRP1, CAS2, TYRP, TYRRP, TYRP1 |
| Swissprot | |
| Cellular Localization | Melanosome membrane |
| Tissue Specificity | Pigment cells. |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Epigenetics and Nuclear Signaling, Cancer, Tags and Cell Markers, Cell Biology, Signal Transduction, Tumor Biomarkers. |
| Clone | TA99 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | Tyrosinase-related protein 1, also known as TYRP1 or MEL-5, is an enzyme found in melanocytes and is involved in the synthesis of melanin. TYRP1 stabilizes tyrosinase and modulates its catalytic activity. It is also involved in the maintenance of melanosome structures, as well as the proliferation and cell death of melanocytes. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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